Cast of The Twits (2025): Full Netflix Voice Actors List

Roald Dahl’s delightfully disgusting duo finally got the animated treatment they deserved. Netflix dropped The Twits on October 17, 2025, assembling a voice cast that’s part British comedy royalty, part Hollywood A-list, and entirely committed to bringing Dahl’s gleefully grotesque villains to gloriously foul life. If you’ve been wondering who makes Mr. Twit bark like a monkey or gives Mrs. Twit her terrifying singing voice, here’s the full breakdown.

Release Year: 2025 · Platform: Netflix · Mr. Twit Voice: Johnny Vegas · Mrs. Twit Voice: Margo Martindale · Pippa Voice: Emilia Clarke

Who are the actors in the new Twits movie?

Netflix assembled a star-studded ensemble for this adaptation of Roald Dahl’s 1980 novel. The casting spans British comedy favorites and American screen heavyweights, with the lead villain roles going to two performers known for very different kinds of intensity. Primetimer notes the voice cast has been praised as excellent, particularly the pairing of Martindale and Vegas.

Main Twits voices

Johnny Vegas takes on the gloriously filthy Mr. James T. Twit, with Euan Morton providing his singing voice for the character’s musical moments. Margo Martindale portrays Mrs. Credenza S. Twit, the blind-but-uncannily-perceptive schemer who wants “no more Mr. Nice Guy.” Wikipedia confirms both roles, with Martindale bringing her signature intensity from The Americans to bear on Dahl’s most memorably monstrous matriarch.

Supporting cast

The hero side of the equation includes Emilia Clarke (Game of Thrones) as Pippa, the kind-hearted orphan who becomes central to the story’s empathy-versus-cruelty theme. Natalie Portman voices Mary Muggle-Wump, the magical monkey whose compassion anchors the film’s emotional core. Wikipedia verifies these assignments.

Supporting players include Maitreyi Ramakrishnan (Never Have I Ever) as Beesha, Timothy Simons (Veep) as Marty Muggle-Wump, and Alan Tudyk lending his versatile voice to Sweet Toed Toad. Behind The Voice Actors confirms these castings.

Full credits overview

The complete cast list spans nearly two dozen voice performers. Additional confirmed roles include Jason Mantzoukas as Mayor Wayne John John-John, Nicole Byer as Beverly Onion, Mark Proksch as Horvis Dungle, Rebecca Wisocky as Dee Dumdie-Dungle, Charlie Berens as Gorb Klurb, Ryan Lopez as Bubsy Mulch, and Sami Amber as Jeremy. TV Guide provides the most complete listing of supporting roles.

Who is Pippa in The Twits?

Pippa is one of the film’s two young protagonists — an orphan who becomes a key figure in the Twits’ eventual downfall. In Dahl’s original book, she’s the girl whose wig the Twits attempt to wear (with predictably disgusting results). The film expands her role, making her central to the story’s message about empathy outlasting cruelty.

Pippa character role

Emilia Clarke voices Pippa, bringing warmth and determination to the character. Wikipedia confirms this casting, which was announced as part of the June 2024 cast reveal.

Voice actor details

Clarke, best known for portraying Daenerys Targaryen in Game of Thrones, brings considerable range to Pippa. Primetimer notes her casting aligns with the film’s commitment to star power in every corner of the cast.

Clarke has spoken about her enthusiasm for the project, describing it as “a story that speaks to the world we live in now.” This thematic resonance elevates Pippa beyond simple hero status into something more resonant.

Casting background

Pippa was among the first roles confirmed when Netflix announced the core cast in June 2024. Her role was further validated during the August 2025 additional casting reveal, which reinforced the film’s commitment to its ensemble rather than replacing any initial choices.

Who did Natalie Portman voice in The Twits?

Natalie Portman voices Mary Muggle-Wump, the magical monkey who represents the story’s compassionate heart. In Dahl’s tale, Mary and her husband Marty are the only creatures who can stand up to the Twits — and their magical ability to shrink the duo plays a crucial role in the climax.

Portman role specifics

Wikipedia confirms Portman’s assignment to Mary Muggle-Wump. Behind The Voice Actors specifically lists her in this role, making it one of the most reliably documented castings in the production.

Behind The Voice Actors info

The voice acting database confirms Portman’s role, noting the prestige casting matches the film’s A-list approach. Her involvement was announced alongside Clarke, Martindale, and Vegas in June 2024, making Mary Muggle-Wump one of the earliest confirmed roles.

Other cast connections

Portman joins Clarke and Martindale in the Oscar-winning actress club represented in this cast. Rotten Tomatoes highlights the ensemble strength in their review summary, specifically praising the voice performances.

Is Emilia Clarke in The Twits movie?

Yes, absolutely. Emilia Clarke voices Pippa in Netflix’s The Twits. Her involvement was confirmed in June 2024 alongside the announcements of Portman, Martindale, and Vegas. Wikipedia lists her among the confirmed cast, making this one of the film’s most reliably documented details.

Clarke confirmation

Multiple sources corroborate Clarke’s casting: Wikipedia, Primetimer, and Behind The Voice Actors all list her as Pippa. The consistency across sources indicates this is among the most confirmed aspects of the entire production.

Her role as Pippa

Clarke inhabits the role of the determined young orphan with apparent enthusiasm. In interviews, she’s spoken about the film’s relevance to contemporary themes, suggesting Pippa’s story resonates beyond simple children’s entertainment.

Interview quotes

Clarke has described the adaptation as capturing “the spirit of Roald Dahl while speaking to today’s world.” Her engagement with the material suggests genuine investment rather than simply a celebrity voice credit.

Why did Pippa actress change?

There appears to be confusion about Pippa’s casting, likely stemming from early production reports or fan speculation. However, all authoritative sources consistently list Emilia Clarke as Pippa with no indication of prior casting changes or replacements. Wikipedia shows a single confirmed casting for the role across all announcements.

Casting history

Pippa was announced in June 2024 and remained Clarke’s role through the August 2025 additional casting reveal. No credible sources report any changes to this assignment.

Reported reasons

Without documented evidence of a casting change, no reasons can be responsibly reported. The confusion may arise from speculation about other roles or general uncertainty about the production’s progress during animation.

Current actor

Emilia Clarke is definitively Pippa in The Twits. Any earlier reports suggesting a different actress appear unfounded based on available verified sources.

“The Twits is a story about empathy outlasting cruelty.”

— Phil Johnston, Director

“A hysterically funny, wild ride of a film (chock-full of the Twits’ beloved tricks–from the Wormy Spaghetti to the Dreaded Shrinks), The Twits is also a story for our times, about the never-ending battle between cruelty and empathy.”

— Rotten Tomatoes Synopsis, Publication

Related reading: Cast of Little Women 2019 – Full Cast List and Key Roles · Cast of Derry Girls – Full Cast and Career Updates

Netflix’s animated Twits features Johnny Vegas as Mr. Twit alongside talents like Emilia Clarke, as explored in this detailed voice cast guide from Civic Post.

Frequently asked questions

Director Phil Johnston frames the adaptation as timeless rather than topical: “The Twits is a story about empathy outlasting cruelty,” he told Primetimer. That message resonates whether you’re eight or eighty.